Article
Outcome of metastatic breast cancer in selected women with or without deleterious BRCA mutations.
Clinical & experimental metastasis - 1 Jun 2013
Bayraktar S, Gutierrez-Barrera A M, Lin H, Elsayegh N, Tasbas T, Litton J K, Ibrahim N K, Morrow P K, Green M, Valero V, Booser D J, Hortobagyi G N, Arun B K
Abstract excerpt
The aim of this study was to compare the time-to progression and overall survival (OS) in patients with metastatic breast cancer (MBC) with and without deleterious BRCA1/2 mutations. 195 women with MBC who were referred for BRCA genetic testing between 1997 and 2011 were included in the study. Logistic regression models and Cox proportional hazards models were fit to determine the associations between clinical...
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