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Article

Incidence and outcome of BRCA mutations in unselected patients with triple receptor-negative breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2011

Gonzalez-Angulo Ana M, Timms Kirsten M, Liu Shuying, Chen Huiqin, Litton Jennifer K, Potter Jennifer, Lanchbury Jerry S, Stemke-Hale Katherine, Hennessy Bryan T, Arun Banu K, Hortobagyi Gabriel N, Do Kim-Anh, Mills Gordon B, Meric-Bernstam Funda

Abstract excerpt

PURPOSE: To investigate the incidence of germline and somatic BRCA1/2 mutations in unselected patients with triple-negative breast cancer (TNBC) and determine the prognostic significance of carrying a mutation. METHODS: DNA was obtained from 77 TNBC and normal tissues. BRCA1/2 exons/flanking regi...

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Identifiers

PMID: 21233401
DOI: 10.1158/1078-0432.CCR-10-2560
PMCID: PMC3048924

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21233401-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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