Article
ADAMTS14 Gene Polymorphism and Environmental Risk in the Development of Oral Cancer.
PloS one - 1 Jan 2016
Su Shih-Chi, Hsieh Ming-Ju, Liu Yu-Fan, Chou Ying-Erh, Lin Chiao-Wen, Yang Shun-Fa
Abstract excerpt
BACKGROUND: Oral cancer is a common malignancy that is shown to be causally associated with hereditary and acquired factors. ADAMTS14 is a member of the ADAMTS (a disintegrin-like and metalloproteinase domain with thrombospondin motifs) metalloproteinase family that plays an important role in extracellular matrix (ECM) assembly and degradation. Elevation or deficiency of certain ADAMTS proteinases has been known...
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