Article
Impacts of CA9 gene polymorphisms and environmental factors on oral-cancer susceptibility and clinicopathologic characteristics in Taiwan.
PloS one - 1 Jan 2012
Chien Ming-Hsien, Yang Jia-Sin, Chu Yin-Hung, Lin Chien-Huang, Wei Lin-Hung, Yang Shun-Fa, Lin Chiao-Wen
Abstract excerpt
BACKGROUND: In Taiwan, oral cancer has causally been associated with environmental carcinogens. Carbonic anhydrase 9 (CA9) is reportedly overexpressed in several types of carcinomas and is generally considered a marker of malignancy. The current study explored the combined effect of CA9 gene polymorphisms and exposure to environmental carcinogens on the susceptibility of developing oral squamous cell carcinoma...
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