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Functional AGXT2 SNP rs37369 Variant Is a Risk Factor for Diabetes Mellitus: Baseline Data From the Aidai Cohort Study in Japan.

Canadian journal of diabetes - 1 Dec 2022

Kumon Hiroshi, Miyake Yoshihiro, Yoshino Yuta, Iga Jun-Ichi, Tanaka Keiko, Senba Hidenori, Kimura Eizen, Higaki Takashi, Matsuura Bunzo, Kawamoto Ryuichi, Ueno Shu-Ichi

Abstract excerpt

OBJECTIVES: The relationship between alanine-glyoxylate aminotransferase 2 (AGXT2) single-nucleotide polymorphisms (SNPs) and diabetes mellitus (DM) has not been investigated. Therefore, we performed a case-control study to examine this relationship. METHODS: The study subjects included 2,390 Japanese men and women aged 34 to 88 years. In total, 190 cases were defined as having a fasting plasma glucose level...

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PMID: 35961823
DOI: 10.1016/j.jcjd.2022.06.004

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