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Article

Time to re‐consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma

15 May 2014

Abstract excerpt

The BRAF V600E mutation, resulting from the BRAFT1799A transversion, is the most common genetic mutation in papillary thyroid carcinoma (PTC), with a mean frequency close to 50% among all cases. A large number of studies in the past decade have tried to dissect the relevance and the function of the V600E mutation in controlling oncogenesis and progression of thyroid cancer. However, several works published in the...

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PMID: 24828987
DOI: 10.1002/ijc.28976

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