Article
Association of virulent genotypes and phylogenetic origins of Helicobacter pylori with gastric cancer.
The Journal of international medical research - 1 Aug 2014
Wang Lili, Zhan Shuhui, Zhou Jianhua, Huang Jingjing, Yu Xinjuan, Dong Kaixin, Dong Quanjiang
Abstract excerpt
OBJECTIVE: To investigate the association between the genotypes, sequence variations and phylogenetic origins of strains of Helicobacter pylori with gastric cancer in Chinese patients. METHODS: Strains of H. pylori were isolated from patients with chronic gastritis and gastric cancer. Genotypes of the cagA and vacA genes were determined using polymerase chain reaction. Sequence analysis was used to detect...
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