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Genomic characterization of clinical Helicobacter pylori strains from Korea: insights into phylogeny, pan-genome structure, and virulence factors.

BMC microbiology - 11 May 2026

Jung Hi Eun, Bang Chang Seol, Ahn Ji Yong, Jung Hwoon-Yong, Lee Sun Mi, Kim So Won, Chae Dong Woo, Gong Eun Jeong

Abstract excerpt

BACKGROUND: Helicobacter pylori (H. pylori) is a globally prevalent gastric pathogen whose genetic diversity and virulence contribute to the varied clinical outcomes. Whole-genome sequencing has revolutionized microbial genomics by allowing high-resolution analyses to obtain insights into the evolution of pathogenic organisms; however, few studies have specifically focused on strains from Korea, where H. pylori...

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PMID: 42108439
DOI: 10.1186/s12866-026-05130-4
PMCID: PMC13330472

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