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Article

Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan.

Journal of clinical microbiology - 1 Aug 2005

Yamazaki Shiho, Yamakawa Akiyo, Okuda Tomoyuki, Ohtani Masahiro, Suto Hiroyuki, Ito Yoshiyuki, Yamazaki Yukinao, Keida Yoshihide, Higashi Hideaki, Hatakeyama Masanori, Azuma Takeshi

Abstract excerpt

Colonization of the stomach mucosa by Helicobacter pylori is a major cause of acute and chronic gastric pathologies in humans. Several H. pylori virulence genes that may play a role in its pathogenicity have been identified. The most important determinants are vacA and cagA in the cag pathogenicity island (cagPAI) genes. In the present study, to consider the association of molecular genetics between vacA and the...

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Identifiers

PMID: 16081930
DOI: 10.1128/JCM.43.8.3906-3916.2005
PMCID: PMC1233989

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Source receipt: pubmed, retrieved 7 Sept 2026.

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