Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan.

doi:10.1128/JCM.43.8.3906-3916.2005

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Article

Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan.

Journal of clinical microbiology - 1 Aug 2005

Yamazaki Shiho, Yamakawa Akiyo, Okuda Tomoyuki, Ohtani Masahiro, Suto Hiroyuki, Ito Yoshiyuki, Yamazaki Yukinao, Keida Yoshihide, Higashi Hideaki, Hatakeyama Masanori, Azuma Takeshi

Abstract excerpt

Colonization of the stomach mucosa by Helicobacter pylori is a major cause of acute and chronic gastric pathologies in humans. Several H. pylori virulence genes that may play a role in its pathogenicity have been identified. The most important determinants are vacA and cagA in the cag pathogenici...

Topics

Amino Acid Sequence
Antigens, Bacterial
Bacterial Proteins
Base Sequence
Genetic Variation
Helicobacter pylori
Humans
Molecular Sequence Data
Peptic Ulcer
Phylogeny

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Identifiers

PMID: 16081930
DOI: 10.1128/JCM.43.8.3906-3916.2005
PMCID: PMC1233989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16081930-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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