Article
Distribution of Helicobacter pylori virulence markers in patients with gastroduodenal diseases in a region at high risk of gastric cancer.
Microbial pathogenesis - 1 Jan 2000
Wang Ming-yi, Chen Cheng, Gao Xiao-zhong, Li Jie, Yue Jing, Ling Feng, Wang Xiao-chun, Shao Shi-he
Abstract excerpt
ABSTRACT BACKGROUND: Helicobacter pylori (H. pylori) is a major human pathogen that is responsible for various gastroduodenal diseases. We investigated the prevalence of H. pylori virulence markers in a region at high risk of gastric cancer. METHODS: One hundred and sixteen H. pylori strains were isolated from patients with gastroduodenal diseases. cagA, the cagA 3' variable region, cagPAI genes, vacA, and dupA...
Topics
- DNA, Bacterial
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Peptic Ulcer
- Polymerase Chain Reaction
- Sequence Analysis, DNA
- Stomach Neoplasms
- Virulence Factors
