Integrative profiling of Helicobacter pylori clinical isolates: virulence genes, antimicrobial susceptibility and genetic diversity in gastric cancer risk stratification.

Abstract excerpt

Background . Helicobacter pylori infection is a major risk factor for gastric cancer (GC), especially in East Asia. However, the mechanisms through which bacterial strain heterogeneity contributes to GC risk remain poorly understood. This study aims to elucidate the roles of specific virulence factors, antibiotic resistance profiles and genetic variations in H. pylori in GC development.Methods. We integrated host...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biofilms
• Share to Drug Resistance, Multiple, Bacterial