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Phenotypic and functional changes induced in hematopoietic stem/progenitor cells after gamma-ray radiation exposure.

Stem cells (Dayton, Ohio) - 1 Jun 2009

Simonnet Arthur J, Nehmé Johnny, Vaigot Pierre, Barroca Vilma, Leboulch Philippe, Tronik-Le Roux Diana

Abstract excerpt

Ionizing radiation (IR) exposure causes rapid and acute bone marrow (BM) suppression that is reversible for nonlethal doses. Evidence is accumulating that IR can also provoke long-lasting residual hematopoietic injury. To better understand these effects, we analyzed phenotypic and functional changes in the stem/progenitor compartment of irradiated mice over a 10-week period. We found that hematopoietic stem cells...

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PMID: 19489102
DOI: 10.1002/stem.66

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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