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Article

Detecting the spectrum of multigene mutations in non-small cell lung cancer by Snapshot assay.

Chinese journal of cancer - 1 Jul 2014

Su Jian, Zhang Xu-Chao, An She-Juan, Zhong Wen-Zhao, Huang Ying, Chen Shi-Liang, Yan Hong-Hong, Chen Zhi-Hong, Guo Wei-Bang, Huang Xiao-Sui, Wu Yi-Long

Abstract excerpt

As molecular targets continue to be identified and more targeted inhibitors are developed for personalized treatment of non-small cell lung cancer (NSCLC), multigene mutation determination will be needed for routine oncology practice and for clinical trials. In this study, we evaluated the sensitivity and specificity of multigene mutation testing by using the Snapshot assay in NSCLC. We retrospectively reviewed a...

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Identifiers

PMID: 24823994
DOI: 10.5732/cjc.013.10195
PMCID: PMC4110467

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EGFR
KRAS
PTEN
BRAF
NRAS

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