Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: a prospective, single-institute study.

doi:10.1002/cncr.28604

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Article

Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: a prospective, single-institute study.

Cancer - 15 May 2014

Serizawa Masakuni, Koh Yasuhiro, Kenmotsu Hirotsugu, Isaka Mitsuhiro, Murakami Haruyasu, Akamatsu Hiroaki, Mori Keita, Abe Masato, Hayashi Isamu, Taira Tetsuhiko, Maniwa Tomohiro, Takahashi Toshiaki, Endo Masahiro, Nakajima Takashi, Ohde Yasuhisa, Yamamoto Nobuyuki

Abstract excerpt

BACKGROUND: Integration of mutational profiling to identify driver genetic alterations in a clinical setting is necessary to facilitate personalized lung cancer medicine. A tumor genotyping panel was developed and the Shizuoka Lung Cancer Mutation Study was initiated as a prospective tumor genotyping study. This study reports the frequency of driver genetic alterations in Japanese lung adenocarcinoma patients,...

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