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Article

Comparison of Next-Generation Sequencing, Quantitative PCR, and Sanger Sequencing for Mutation Profiling of EGFR, KRAS, PIK3CA and BRAF in Clinical Lung Tumors.

Clinical laboratory - 1 Jan 2016

Gao Jie, Wu Huanwen, Shi Xiaohua, Huo Zhen, Zhang Jing, Liang Zhiyong

Abstract excerpt

BACKGROUND: The clinical application of next-generation sequencing technologies has offered a more comprehensive understanding of the mutational profile of tumor samples. The study was aimed to evaluate the feasibility of the NextDaySeq-Lung panel, which is an NGS-based assay for mutation analysis of key driver genes in lung cancer, in a clinical setting. METHODS: A total of 138 FFPE samples of non-small cell...

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Identifiers

PMID: 27215089
DOI: 10.7754/clin.lab.2015.150837

Genes

BRAF
EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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