Article
EGFR and KRAS mutational analysis in a large series of Italian non-small cell lung cancer patients: 2,387 cases from a single center.
Oncology reports - 1 Aug 2016
Giannini Riccardo, Lupi Cristiana, Sensi Elisa, Alì Greta, Proietti Agnese, Boldrini Laura, Servadio Adele, Giordano Mirella, Macerola Elisabetta, Bruno Rossella, Borrelli Nicla, Chella Antonio, Melfi Franca, Lucchi Marco, Ribechini Alessandro, Vasile Enrico, Cappuzzo Federico, Mussi Alfredo, Fontanini Gabriella
Abstract excerpt
Activating EGFR mutations are important genetic alterations that have strong therapeutic implications for non-small cell lung cancer (NSCLC) patients. However, the role of KRAS mutations in this process is still under evaluation. Here, we report on the feasibility of a large‑scale EGFR and KRAS mutation analysis in the daily routine of a single center. NSCLCs from 2,387 patients were screened for EGFR and KRAS...
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