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Article

Discrimination of pseudogene and parental gene DNA methylation using allelic bisulfite sequencing.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Hesson Luke B, Ward Robyn L

Abstract excerpt

Determining the methylation status of genes with pseudogenes can be technically challenging due to sequence homology. High sequence homology can result in the amplification of both pseudogene and parental gene alleles, potentially leading to data misinterpretation. Allelic bisulfite sequencing allows for detection of the methylation status of individual alleles at nucleotide resolution and represents the most...

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PMID: 24823784
DOI: 10.1007/978-1-4939-0835-6_18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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