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Article

Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions.

PloS one - 1 Jan 2014

Evans Daniel S, Calton Melissa A, Kim Mee J, Kwok Pui-Yan, Miljkovic Iva, Harris Tamara, Koster Annemarie, Liu Yongmei, Tranah Gregory J, Ahituv Nadav, Hsueh Wen-Chi, Vaisse Christian

Abstract excerpt

Common genetic variants 3' of MC4R within two large linkage disequilibrium (LD) blocks spanning 288 kb have been associated with common and rare forms of obesity. This large association region has not been refined and the relevant DNA segments within the association region have not been identified. In this study, we investigated whether common variants in the MC4R gene region were associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24820477
DOI: 10.1371/journal.pone.0096805
PMCID: PMC4018404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions.PMID 24820477Read ↗

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