Single nucleotide polymorphism in ATM gene, cooking oil fumes and lung adenocarcinoma susceptibility in Chinese female non-smokers: a case-control study.

doi:10.1371/journal.pone.0096911

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Single nucleotide polymorphism in ATM gene, cooking oil fumes and lung adenocarcinoma susceptibility in Chinese female non-smokers: a case-control study.

PloS one - 1 Jan 2014

Shen Li, Yin Zhihua, Wu Wei, Ren Yangwu, Li Xuelian, Zhou Baosen

Abstract excerpt

BACKGROUND: The ataxia-telangiectasia mutated (ATM) gene plays an important role in the DNA double-strand breaks repair pathway. Single nucleotide polymorphisms (SNPs) of DNA repair genes are suspected to influence the risk of lung cancer. This study aimed to investigate the association between the ATM -111G>A (rs189037) polymorphism, environmental risk factors and the risk of lung adenocarcinoma in Chinese...

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PMID: 24819391
DOI: 10.1371/journal.pone.0096911
PMCID: PMC4018408

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