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The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations.

Human genetics - 1 Mar 2012

Ahn Myung-Ju, Won Hong-Hee, Lee Jeeyun, Lee Seung-Tae, Sun Jong-Mu, Park Yeon Hee, Ahn Jin Seok, Kwon O Jung, Kim Hojoong, Shim Young Mog, Kim Jhingook, Kim Kwhanmien, Kim Yeul Hong, Park Jae Yong, Kim Jong-Won, Park Keunchil

Abstract excerpt

The proportion of never smoker non-small cell lung cancer (NSCLC) in Asia is about 30-40%. Despite the striking demographics and high prevalence of never smoker NSCLC, the exact causes still remain undetermined. Although several genome wide association (GWA) studies were conducted to find susceptibility loci for lung cancer in never smokers, no regions were replicated except for 5p15.33, suggesting locus...

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PMID: 21866343
DOI: 10.1007/s00439-011-1080-z

Genes

APCDD1
DAB1
NAPG

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