Article
XRCC1 polymorphisms, cooking oil fume and lung cancer in Chinese women nonsmokers.
Lung cancer (Amsterdam, Netherlands) - 1 Nov 2008
Li Mingchuan, Yin Zhihua, Guan Peng, Li Xuelian, Cui Zeshi, Zhang Jun, Bai Weijun, He Qincheng, Zhou Baosen
Abstract excerpt
X-ray repair cross-complementing group 1 (XRCC1) is one of the major DNA repair proteins involved in the base excision repair (BER) and single-strand break repair (SSBR) pathway. Single nucleotide polymorphisms (SNPs) in XRCC1 may alter protein function and repair capacity, thus lead to genetic instability and carcinogenesis. To establish our understanding of possible relationships between XRCC1 polymorphisms...
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