Article
Skin pH, atopic dermatitis, and filaggrin mutations.
Dermatitis : contact, atopic, occupational, drug - 1 Jan 2000
Bandier Josefine, Johansen Jeanne Duus, Petersen Lars Jelstrup, Carlsen Berit Christina
Abstract excerpt
BACKGROUND: The acidic pH of the skin plays a role in antimicrobial defense by regulating the bacterial skin flora and aspects of barrier. Filaggrin is a co-factor in maintaining a low skin pH because of its degradation into acidic amino acids. Accordingly, lack of filaggrin due to filaggrin mutations may influence skin pH. OBJECTIVE: We aimed to determine the epidermal pH in different groups stratified by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
