A dimer is the minimal proton-conducting unit of the influenza a virus M2 channel.

Abstract excerpt

When influenza A virus infects host cells, its integral matrix protein M2 forms a proton-selective channel in the viral envelope. Although X-ray crystallography and NMR studies using fragment peptides have suggested that M2 stably forms a tetrameric channel irrespective of pH, the oligomeric states of the full-length protein in the living cells have not yet been assessed directly. In the present study, we...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amantadine
• Share to CHO Cells
• Share to Cricetulus