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Article

Treatment-related Neuroendocrine Prostate Carcinoma—Diagnostic and Molecular Correlates

15 Jan 2024

Abstract excerpt

Treatment-related neuroendocrine prostate cancer is a distinctive category of prostate cancer that arises after intensive suppression of the androgen receptor by next-generation therapeutic inhibition of androgen receptor signaling. The biological processes that set in motion the series of events resulting in transformation of adenocarcinoma to neuroendocrine carcinoma include genomic (loss of tumor suppressors...

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PMID: 38223983
DOI: 10.1097/pap.0000000000000431

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