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Article

The impact of 5-HTTLPR on acute serotonin transporter blockade by escitalopram on emotion processing: preliminary findings from a randomised, crossover fMRI study.

The Australian and New Zealand journal of psychiatry - 1 Dec 2014

Outhred Tim, Das Pritha, Dobson-Stone Carol, Felmingham Kim L, Bryant Richard A, Nathan Pradeep J, Malhi Gin S, Kemp Andrew H

Abstract excerpt

OBJECTIVE: Benefit from antidepressant treatment such as selective serotonin reuptake inhibitors (SSRIs) may depend on individual differences in acute effects on neural emotion processing. The short ('S') allele of the serotonin transporter (5-HTT)-linked polymorphic region (5-HTTLPR) is associated with both negative emotion processing biases and poorer treatment outcomes. Therefore, the aim of the present study...

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Identifiers

PMID: 24810870
DOI: 10.1177/0004867414533837

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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