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Article

Enhancement of DNA vaccine potency against legumain.

Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jun 2014

Smahel Michal, Duskova Martina, Polakova Ingrid, Musil Jan

Abstract excerpt

The asparaginyl endopeptidase legumain that is overexpressed in M2-polarized tumor-associated macrophages has been identified as a suitable target for elimination of these cells supporting tumor progression. To enhance the efficacy of DNA immunization against legumain, we performed several modifi...

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Source

Identifiers

PMID: 24810641
DOI: 10.1097/CJI.0000000000000040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24810641-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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