Article

Enhanced the immunity activity of HPV16 DNA vaccine by the combination CpG oligonucleotides adjuvant cloned into plasmid backbone and IL-28B gene adjuvant

2024-05-13

Abstract excerpt

<title>Abstract</title> <p>Therapeutic human papillomavirus (HPV) DNA vaccine is an attractive option to control existed HPV infection and related lesions. The two early viral oncoproteins, E6 and E7, are continuously expressed in most HPV-related pre- and cancerous cells, and are ideal targets for therapeutic vaccines. We have previously developed HPV 16 DNA vaccines encoding mE7/HSP70, which generated significa...

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Literature Corpus work: fc46f6e1-84b0-54e7-aed5-c247ac368d9f
DOI: 10.21203/rs.3.rs-4338069/v1

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