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Article

Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis

8 May 2014

Abstract excerpt

Mycobacterium tuberculosis bacilli display two signature features: acid-fast staining and the capacity to induce long-term latent infections in humans. However, the mechanisms governing these two important processes remain largely unknown. Ser/Thr phosphorylation has recently emerged as an important regulatory mechanism allowing mycobacteria to adapt their cell wall structure/composition in response to their...

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PMID: 24809459
DOI: 10.1371/journal.ppat.1004115

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