Article
The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases.
Molecular & cellular proteomics : MCP - 1 Jun 2010
Schmidl Sebastian R, Gronau Katrin, Pietack Nico, Hecker Michael, Becher Dörte, Stülke Jörg
Abstract excerpt
Mycoplasma pneumoniae belongs to the Mollicutes, the group of organisms with the smallest genomes that are capable of host-independent life. These bacteria show little regulation in gene expression, suggesting an important role for the control of protein activities. We have studied protein phosphorylation in M. pneumoniae to identify phosphorylated proteins. Two-dimensional gel electrophoresis and mass...
Topics
- Amino Acid Sequence
- Bacterial Adhesion
- Bacterial Proteins
- Conserved Sequence
- Enzyme Activation
- Glycolysis
- Mass Spectrometry
- Molecular Sequence Data
- Mutation
- Mycoplasma pneumoniae
- Phosphoproteins
- Phosphorylation
- Protein Serine-Threonine Kinases