Requirement for <i>kasB</i> in <i>Mycobacterium</i> mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy

Abstract excerpt

Mycobacterium tuberculosis infects one-third of the world's population and causes two million deaths annually. The unusually low permeability of its cell wall contributes to the ability of M. tuberculosis to grow within host macrophages, a property required for pathogenesis of infection. Mycobacterium marinum is an established model for discovering genes involved in mycobacterial infection. Mycobacterium marinum...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antibiotic Resistance in Bacteria
• Share to Mycobacterium research and diagnosis
• Share to Tuberculosis Research and Epidemiology