Article
Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America - 20 May 2014
Song Junfang, McColl James, Camp Esther, Kennerley Niki, Mok Gi Fay, McCormick Dominique, Grocott Timothy, Wheeler Grant N, Münsterberg Andrea E
Abstract excerpt
In vertebrate embryos, cardiac progenitor cells (CPCs) undergo long-range migration after emerging from the primitive streak during gastrulation. Together with other mesoderm progenitors, they migrate laterally and then toward the ventral midline, where they form the heart. Signals controlling the migration of different progenitor cell populations during gastrulation are poorly understood. Several pathways are...
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