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Article

Bmp signaling exerts opposite effects on cardiac differentiation.

Circulation research - 17 Feb 2012

de Pater Emma, Ciampricotti Metamia, Priller Florian, Veerkamp Justus, Strate Ina, Smith Kelly, Lagendijk Anne Karine, Schilling Thomas F, Herzog Wiebke, Abdelilah-Seyfried Salim, Hammerschmidt Matthias, Bakkers Jeroen

Abstract excerpt

RATIONALE: The importance for Bmp signaling during embryonic stem cell differentiation into myocardial cells has been recognized. The question when and where Bmp signaling in vivo regulates myocardial differentiation has remained largely unanswered. OBJECTIVE: To identify when and where Bmp signaling regulates cardiogenic differentiation. METHODS AND RESULTS: Here we have observed that in zebrafish embryos, Bmp...

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Identifiers

PMID: 22247485
DOI: 10.1161/CIRCRESAHA.111.261172
PMCID: PMC4924880

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