Article
β-Catenin is required for hair-cell differentiation in the cochlea.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 May 2014
Shi Fuxin, Hu Lingxiang, Jacques Bonnie E, Mulvaney Joanna F, Dabdoub Alain, Edge Albert S B
Abstract excerpt
The development of hair cells in the auditory system can be separated into steps; first, the establishment of progenitors for the sensory epithelium, and second, the differentiation of hair cells. Although the differentiation of hair cells is known to require the expression of basic helix-loop-helix transcription factor, Atoh1, the control of cell proliferation in the region of the developing cochlea that will...
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