Schwann cell p75 neurotrophin receptor modulates small fiber degeneration in diabetic neuropathy

Abstract excerpt

Abstract Diabetic neuropathy has an incidence as high as 50% of diabetic patients and is characterized by damage to neurons, Schwann cells and blood vessels within the peripheral nervous system. The low‐affinity neurotrophin receptor p75 (p75NTR), particularly expressed by the Schwann cells in the peripheral nerve, has previously been reported to play a role in developmental myelination and cell survival/death....

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