Article
STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis.
The EMBO journal - 2 Jun 2014
Fukuda Tomoyuki, Fukuda Nanaho, Agostinho Ana, Hernández-Hernández Abrahan, Kouznetsova Anna, Höög Christer
Abstract excerpt
Cohesion between sister chromatids in mitotic and meiotic cells is promoted by a ring-shaped protein structure, the cohesin complex. The cohesin core complex is composed of four subunits, including two structural maintenance of chromosome (SMC) proteins, one α-kleisin protein, and one SA protein. Meiotic cells express both mitotic and meiosis-specific cohesin core subunits, generating cohesin complexes with...
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