Article
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
The EMBO journal - 2 Jun 2014
Chaya Taro, Omori Yoshihiro, Kuwahara Ryusuke, Furukawa Takahisa
Abstract excerpt
Cilia and flagella are formed and maintained by intraflagellar transport (IFT) and play important roles in sensing and moving across species. At the distal tip of the cilia/flagella, IFT complexes turn around to switch from anterograde to retrograde transport; however, the underlying regulatory mechanism is unclear. Here, we identified ICK localization at the tip of cilia as a regulator of ciliary transport. In...
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