Article
Rapid deep sequencing of patient-derived HIV with ion semiconductor technology.
Journal of virological methods - 1 Apr 2013
Chang Max W, Oliveira Glenn, Yuan Jinyun, Okulicz Jason F, Levy Samuel, Torbett Bruce E
Abstract excerpt
The development of next-generation sequencing technologies has facilitated the study of HIV drug resistance evolution. However, the high capacity and per-run cost of many sequencers is not ideal for viral sequencing unless many samples are analyzed simultaneously. Ion semiconductor sequencing has recently emerged as a flexible, lower-cost alternative with short runtime. This paper describes the use of Ion Torrent...
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