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Article

A candidate gene study of CLEC16A does not provide evidence of association with risk for anti-CCP-positive rheumatoid arthritis.

Genes and immunity - 1 Sept 2010

Bronson P G, Ramsay P P, Seldin M F, Gregersen P K, Criswell L A, Barcellos L F

Abstract excerpt

CLEC16A, a putative immunoreceptor, was recently established as a susceptibility locus for type I diabetes and multiple sclerosis. Subsequently, associations between CLEC16A and rheumatoid arthritis (RA), Addison's disease and Crohn's disease have been reported. A large comprehensive and independent investigation of CLEC16A variation in RA was pursued. This study tested 251 CLEC16A single-nucleotide polymorphisms...

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Source

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Identifiers

PMID: 20220768
DOI: 10.1038/gene.2010.7
PMCID: PMC2992879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A candidate gene study of CLEC16A does not provide evidence of association with risk for anti-CCP-positive rheumatoid arthritis.PMID 20220768Read ↗

A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis.Semantic proximity Read ↗

Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus.Semantic proximity Read ↗

From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16ASemantic proximity Read ↗

Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.Semantic proximity Read ↗

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Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia.Semantic proximity Read ↗

Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis.Semantic proximity Read ↗

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