Article
The refinement of genetic predictors of multiple sclerosis.
PloS one - 1 Jan 2014
Disanto Giulio, Dobson Ruth, Pakpoor Julia, Elangovan Ramyiadarsini I, Adiutori Rocco, Kuhle Jens, Giovannoni Gavin
Abstract excerpt
A recent genome wide association study (GWAS) demonstrated that more than 100 genetic variants influence the risk of multiple sclerosis (MS). We investigated what proportion of the general population can be considered at high genetic risk of MS, whether genetic information can be used to predict disease development and how the recently found genetic associations have influenced these estimates. We used summary...
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