Article
Perspectives on the use of multiple sclerosis risk genes for prediction.
PloS one - 1 Jan 2011
Jafari Naghmeh, Broer Linda, van Duijn Cornelia M, Janssens A Cecile J W, Hintzen Rogier Q
Abstract excerpt
OBJECTIVE: A recent collaborative genome-wide association study replicated a large number of susceptibility loci and identified novel loci. This increase in known multiple sclerosis (MS) risk genes raises questions about clinical applicability of genotyping. In an empirical set we assessed the predictive power of typing multiple genes. Next, in a modelling study we explored current and potential predictive...
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