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Article

The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.

The Journal of biological chemistry - 4 Jul 2014

Mohanan Vishnu, Grimes Catherine Leimkuhler

Abstract excerpt

Microbes are detected by the pathogen-associated molecular patterns through specific host pattern recognition receptors. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is an intracellular pattern recognition receptor that recognizes fragments of the bacterial cell wall. NOD...

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Identifiers

PMID: 24790089
DOI: 10.1074/jbc.M114.557686
PMCID: PMC4081938

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24790089-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.PMID 24790089Read ↗

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