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Article

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

The Journal of biological chemistry - 27 Jan 2006

Voss Eske, Wehkamp Jan, Wehkamp Kai, Stange Eduard F, Schröder Jens M, Harder Jürgen

Abstract excerpt

Production of inducible antimicrobial peptides offers a first and rapid defense response of epithelial cells against invading microbes. Human beta-defensin-2 (hBD-2) is an antimicrobial peptide induced in various epithelia upon extracellular as well as intracellular bacterial challenge. Nucleotid...

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Source

Identifiers

PMID: 16319062
DOI: 10.1074/jbc.M511044200

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16319062-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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