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Article

Vps factors are required for efficient transcription elongation in budding yeast.

Genetics - 1 Mar 2013

Gaur Naseem A, Hasek Jiri, Brickner Donna Garvey, Qiu Hongfang, Zhang Fan, Wong Chi-Ming, Malcova Ivana, Vasicova Pavla, Brickner Jason H, Hinnebusch Alan G

Abstract excerpt

There is increasing evidence that certain Vacuolar protein sorting (Vps) proteins, factors that mediate vesicular protein trafficking, have additional roles in regulating transcription factors at the endosome. We found that yeast mutants lacking the phosphatidylinositol 3-phosphate [PI(3)P] kinase Vps34 or its associated protein kinase Vps15 display multiple phenotypes indicating impaired transcription...

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Identifiers

PMID: 23335340
DOI: 10.1534/genetics.112.146308
PMCID: PMC3584001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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