Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.

Genes & development - 15 May 1996

Lee M S, Henry M, Silver P A

Abstract excerpt

The connection between RNA and protein export from the nucleus was examined in the budding yeast Saccharomyces cerevisiae. NPL3 encodes an RNA-binding protein that shuttles in and out of the nucleus. Export of poly(A)+ RNA has been shown previously to be blocked in np13-1 mutants. To understand the role of Np13p in RNA export, we have developed a novel assay that effectively uncouples nuclear protein export from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Biological Transport
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Nuclear Proteins

Share to Saccharomyces cerevisiae Proteins

Share to Temperature

Source

Identifiers

PMID: 8675010
DOI: 10.1101/gad.10.10.1233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.PMID 8675010Read ↗

A yeast protein that bidirectionally affects nucleocytoplasmic transport.Semantic proximity Read ↗

Messenger RNAs are recruited for nuclear export during transcription.Semantic proximity Read ↗

Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export.Semantic proximity Read ↗

The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes.Semantic proximity Read ↗

The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics.Semantic proximity Read ↗

Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3.Semantic proximity Read ↗

The mRNA export factor Npl3 mediates the nuclear export of large ribosomal subunits.Semantic proximity Read ↗

A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport.Semantic proximity Read ↗

Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast.Semantic proximity Read ↗

A conditional yeast mutant deficient in mRNA transport from nucleus to cytoplasm.Semantic proximity Read ↗

mRNA nuclear export and human disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.