Article
Tissue studies in screened first-degree relatives reveal a distinct Crohn's disease phenotype.
Inflammatory bowel diseases - 1 Jun 2014
Sorrentino Dario, Avellini Claudio, Geraci Marco, Dassopoulos Themistocles, Zarifi Dimitra, Vadalaʼ di Prampero Salvatore Francesco, Benevento Gianluca
Abstract excerpt
BACKGROUND: First-degree relatives of patients with Crohn's disease (CD) are at risk of developing the disease with 5% to 15% reported to be affected over time. Yet, a much greater proportion of them (>40%) shows features of "subclinical inflammation" with elevated intestinal inflammatory markers such as fecal calprotectin. The meaning of these findings is unclear in the absence of tissue data. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.