Article
First-degree relatives of early-onset gastric cancer patients show a high risk for gastric cancer: phenotype and genotype profile.
Virchows Archiv : an international journal of pathology - 1 Sept 2013
Marcos-Pinto Ricardo, Dinis-Ribeiro Mário, Carneiro Fátima, Wen Xiaogang, Lopes Carlos, Figueiredo Céu, Machado José Carlos, Ferreira Rui M, Reis Celso A, Canedo Paulo, Durães Cecília, Ferreira José, Pedroto Isabel, Areias Jorge
Abstract excerpt
First-degree relatives (FDR) of early-onset gastric cancer (EOGC) is presumed to be a population with a distinct molecular and phenotypic profile, regarding the prevalence of gastric premalignant conditions and the association with Helicobacter pylori infection and host proinflammatory gene polymorphisms. A case-control study was conducted with FDR of EOGC patients (n = 103) and age and gender matched controls...
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