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Article

Age-dependent alterations of the hippocampal cell composition and proliferative potential in the hAβPPSwInd-J20 mouse.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Fu YuHong, Rusznák Zoltán, Kwok John B J, Kim Woojin Scott, Paxinos George

Abstract excerpt

The J20 mouse expresses human mutant amyloid-β protein precursor (hAβPPSwInd) and is an established transgenic model of Alzheimer's disease (AD). From the age of 5 months, amyloid-β (Aβ) deposits appear in the hippocampus with concomitant increase of AD-associated features. Although changes occurring after the appearance of Aβ deposits have been extensively studied, very little is known about alterations that...

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Identifiers

PMID: 24787919
DOI: 10.3233/JAD-132717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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