Article
MicroRNA-152 targets ADAM17 to suppress NSCLC progression.
FEBS letters - 21 May 2014
Su Yunshu, Wang Yuchang, Zhou Hongmin, Lei Lei, Xu Lijun
Abstract excerpt
MicroRNAs (miRNAs) are a class of small non-coding RNAs that have been suggested to play an essential role in tumorigenesis. In this study, we show that miR-152 is significantly downregulated in non-small cell lung cancer (NSCLC) tissues and cell lines. Restoration of miR-152 significantly reduces proliferation, colony formation, migration and invasion of NSCLC cells. In addition, ADAM metallopeptidase domain 17...
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