Article
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer
2022-11-01
Abstract excerpt
The 5-year survival rate of non-small cell lung cancer (NSCLC) patients is extremely low. microRNAs (miRNAs) are involved in the occurrence of NSCLC. miR-122-5p interacts with wild-type p53 (wtp53), and wtp53 affects tumor growth by inhibiting the mevalonate (MVA) pathway. Therefore, the aim of this study was to evaluate the role of these factors in NSCLC. The role of miR-122-5p and p53 was established in samples...
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Identifiers and source
- Literature Corpus work
- 8c468a48-697a-55ff-8091-dc0400c44fbb
- DOI
- 10.21203/rs.3.rs-2135348/v1
