Article

MicroRNA-148a and -152 counteract RIPK1-mediated apoptosis and necroptosis to promote cancer cell proliferation and cisplatin resistance

2023-01-23

Abstract excerpt

Evasion of cell death is a hallmark of cancer cells. Receptor-interacting protein kinase 1 (RIPK1) is a common mediator in cancer cell death signaling pathways of apoptosis and necroptosis. MicroRNAs (miRNAs) are non-coding small RNAs that are involved in various biological processes such as cell proliferation and death by regulating target genes. Here, we identified miR-148a and miR-152 as suppressors of TNF-indu...

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Literature Corpus work: 923250e0-b60f-5b2e-8e66-bbe2540df0a8
DOI: 10.21203/rs.3.rs-2494581/v1

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